[出典] "Use of CRISPRoff and synthetic Notch to modulate and relay endogenous gene expression programs in engineered cells" Shi S, Hamann CA, Lee JC, Burger JM. Front Bioeng Biotechnol. 2024-06-18. https://doi.org/10.3389/fbioe.2024.1346810 [所属] Vande …
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タグ:細胞系譜
[プロトコル] DNAタイプライターによる分子記録
[出典] Protocol “Molecular recording using DNA Typewriter” Liao H, Choi J, Shendure J. Nat Protoc. 2024-06-06. https://doi.org/10.1038/s41596-024-01003-0 [所属] U Washington (Seattle), , Memorial Sloan Kettering Cancer Center, Brotman Baty Institute for …
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[レビュー] 皮膚における細胞系譜の追跡と発生軌跡のプロファイリングのための遺伝子ツール
[出典] REVIEW "Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin" Nathans JF, Ayers JL, Shendure J, Simpson CL. J Invest Dermatol 2024-04-19. https://doi.org/10.1016/j.jid.2024.02.006 [所属] U Washington Seattle. …
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細胞系譜とトランスクリプトミクスに加えてエピゲノムのプロファイリングも可能にしたマウスモデル系統DARLINを開発
[出典] "A mouse model with high clonal barcode diversity for joint lineage, transcriptomic, and epigenomic profiling in single cells" Li L [..] Wang S-W, Camargo FD. Cell 2023-10-12. https://doi.org/10.1016/j.cell.2023.09.019 [著者所属] Boston Children's …
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CellTag-multiを介して、単一細胞系譜に沿った遺伝子発現とクロマチン・アクセシビリティの同時追跡を実現
[出典] "Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes" Jindal K [..] Morris SA. Nat Biotechnol. 2023-09-25. https://doi.org/10.1038/s41587-023-01931-4 [著者所属] Washington U School …
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