[出典]  "FLASH - a next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences" Quan J, Langelier C, Kuchta A [..] Crawford ED. Nucleic Acids Res 2019-05-22;特許公開 US20190300935A1 Method for finding low abundance ... もっと読む

多剤耐性菌ファージ療法の症例多剤耐性アシネトバクター [出典] "Development and Use of Personalized Bacteriophage-Based Therapeutic Cocktails To Treat a Patient with a Disseminated Resistant Acinetobacter baumannii Infection" Schooley RT, Biswas B et al. A ... もっと読む

[出典] "A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action" Yang JH, Wright SN, Hamblin M [..] Collins JJ. Cell 2019-05-09.背景機械学習によって、生体信号 (biological signals)と実験測定したフェノタイプの相関関係を明らかにす ... もっと読む

ASH Annual Meeting Abstracts (Blood. 2018 132 Spplement 1)から CRISPR/Cas9システムの新たな送達手段:CAR-細胞外小胞 (EV)の腫瘍細胞トロピズムを利用:Targeting Burkitt Lymphoma By CAR-Extracellular Vesicles: A Tropism-Delivery Platform for CRISPR/Cas9 Sys ... もっと読む

[出典] "Synthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers" Ding Y [..] Wood KC, Wang XF. Nat Commun. 2018 Oct 15. 乳癌に対するHER2標的療法はHER2陽性乳癌患者の全生存期間を顕著に伸ばすが、ハイリスク ... もっと読む