crisp_bio

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タグ:CRISPRa

- CRISPR KO, CRISPRiおよびCRISPRa[注] 冠動脈疾患(coronary artery disease:CAD)[出典] "Multimodal CRISPR perturbations of GWAS loci associated with coronary artery disease in vascular endothelial cells" Wünnemann F [..] Lettre G. PLoS Genetics 2023-03-1 ... もっと読む

[出典] "Epigenome editing based on CRISPR/dCas9p300 facilitates transdifferentiation of human fibroblasts into Leydig-like cells" Huang H [..] Jiang H. Exp Cell Res. 2023-03-11. https://doi.org/10.1016/j.yexcr.2023.113551 [著者所属] The First Affiliated H ... もっと読む

[出典] "Massively parallel characterization of CRISPR activator efficacy in human induced pluripotent stem cells and neurons" Wu Q [..] Bassett A. Mol Cell 2023-03-03. https://doi.org/10.1016/j.molcel.2023.02.011 [著者所属] Wellcome Sanger Institute,  C ... もっと読む

[注] HDR(相同組み換え修復)[出典] "Enrichment of transgene integrations by transient CRISPR activation of a silent reporter gene" Mikkelsen NS [..] Bak RO. Mol Ther Methods Clin Dev 2023-02-13 (accepted). https://doi.org/10.1016/j.omtm.2023.02.010 [著者 ... もっと読む

2023-02-17 Nature Communications 誌刊行論文の書誌情報を追記し記事タイトルを「CRISPRaの多用途、高効率なプラットフォーム」から、「CRISPRaの多用途化と効率向上」に改訂。2022-07-30 bioRxivに準拠した初稿[出典] "A versatile, high-efficiency platform for CRISPR-b ... もっと読む

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