crisp_bio

blogging about crisp bio-S&T, especially CRISPR.

タグ:CRISPRa

[出典] "Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries" Clarissa Ribeiro Reily Rocha [..] Carlos Frederico Martins Menck. Cells. 2020-12-01. https://doi.org/10.3390/cells9122573グリオブラストーマのテモゾロミド(TMZ)に対する耐 ... もっと読む

[出典] "Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens" Clements KE [..] Moldovan GL. Nat Commun 2020-11-30. https://doi.org/10.1038/s41467-020-19961-w PARPiは、 ... もっと読む

[出典] "Inhibition of Chlamydial Infection by CRISPR/Cas9-SAM Mediated Enhancement of Human Peptidoglycan Recognition Proteins Gene Expression in HeLa Cells" Bobrovsky PA, Moroz VD, Lavrenova VN, Manuvera VA, Lazarev VN. Biochemistry (Moscow) 2020-11-26. ... もっと読む

[出典] "CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion" Russo GL [..] Götz M. Cell Stem Cell 2020-11-16. https://doi.org/10.1016/j.stem.2020.10.015 損傷・変性した神経組織の置換療法に、アストロ ... もっと読む

[出典] "Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters" Umkehre C [..] Obebauf AC. Nat Biotechnol. 2020-07-27.  Vienna BioCenterを主とする研究グループは今回、CRISPRaをベースとして不均一な細胞集団における特定のクロ ... もっと読む

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