crisp_bio

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タグ:Cas12a

[出典] "Next-generation CRISPR gene-drive systems using Cas12a nuclease" Juste SS,  Okamoto EM, Feng X,  Lopez del Amo V. bioRxiv 2023-02-20 [preprint]. https://doi.org/10.1101/2023.02.20.529271 [著者所属] UT Health Science Center, UCSD. 近年、感染症を ... もっと読む

[出典] "Optimization of Genomewide CRISPR Screens Using AsCas12a and Multi-Guide Arrays" Petiwala S, Modi A [..] Lu C, Flister MJ, Verduzco D. CRISPR J. 2023-02-09. https://doi.org/10.1089/crispr.2022.0093 [著者所属] Abbvie Inc.  CRISPRシステムを利用す ... もっと読む

[注] MAD7はInscripta社が開発しロイヤリティフリーで公開しているEubacterium rectale 由来のCas12a (ErCas12a)[出典] "The CRISPR-Cas12a Platform for Accurate Genome Editing, Gene Disruption, and Efficient Transgene Integration in Human Immune Cells" Mohr M [.. ... もっと読む

[出典] "Profiling the impact of the promoters on CRISPR- Cas12a system in human cells" Li J, Liang Q [..] Huang H. bioRxiv 2023-02-07 (Preprint) https://doi.org/10.1101/2023.02.06.527393; [著者所属] The Third Affiliated Hospital of Southern Medical U, Af ... もっと読む

[注] MECP2  (methyl CpG-binding protein 2) [出典] "Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons" Qian J, Guan X [..] Jaenisch R, Liu XS. Sci Transl Med 2023-01-18. https://doi.org/10.1126/scitranslmed.add4666 [著者所属] Columb ... もっと読む

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