[出典] "CRISPR-Cas12a nucleases function with structurally engineered crRNAs: SynThetic trAcrRNA" Jedrzejczyk DJ [..] Warnecke T, Gill RT. Sci Rep 2022-07-16. https://doi.org/10.1038/s41598-022-15388-z [著者所属] Novo Nordisk Foundation Center for Biosust ...
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タグ:Cas12a
Cas12aバイオセンサーの性能を、レポーターとしてヘアピン型DNAを利用することで向上
[出典] "Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters" Rossetti M [..] Palermo G, Perugino G, Porchetta A. Nucleic Acids Res 2022-07-13. https://doi.org/0.1093/nar/gkac578 [著者所属] U Rome, Institute of Biosciences and ...
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日本脳炎ウイルの野外での検出を実現するワンチューブ反応を介した肉眼での迅速検出を実現
[出典] "A One-tube Rapid Visual CRISPR Assay for The Field Detection of Japanese Encephalitis Virus" Xu B, Gong P [..] Zhang X, Xie S. Virus Res 2022-07-13. https://doi.org/10.1016/j.virusres.2022.198869 [著者所属] Huazhong Agricultural U, Institute of An ...
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CRISPR-Cas12aとCas13a/dによる植物RNAウイルスTMV, TEVおよびPVX感染検査法
[出典] "Diagnostics of Infections Produced by the Plant Viruses TMV, TEV, and PVX with CRISPR-Cas12 and CRISPR-Cas13" Marqués MC [..] Daròs JA, Rodrigo G. ACS Synth Biol 2022-07-06. https://doi.org/10.1093/femsre/fuac035 [著者所属] CSIC─Universitat de ...
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Mn2+がCas12aの活性を高めることを利用して,高感度なMn2+センサーを開発
[出典] "Kinetics Accelerated CRISPR-Cas12a Enabling Live-Cell Monitoring of Mn2+ Homeostasis" Xie S [..] Lei C, Nice Z. Anal Chem. 2022-07-05. https://doi.org/10.1021/acs.analchem.2c01461 [著者所属] Hunan U; Graphical abstract 著者らは,Mn2+がCas12aのc ...
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