[出典] "Terminal deoxynucleotidyl transferase combined CRISPR-Cas12a amplification strategy for ultrasensitive detection of uracil-DNA glycosylase with zero background" Du YC [..] Kong M. Biosens Bioelectron. 2020-10-14.  南開大学 (天津市)の研究グループ ... もっと読む

[出典] "Integrated Micropillar Polydimethylsiloxane Accurate CRISPR Detection System for Viral DNA Sensing" Hass KN [..] Du Ke. Acs Omega 2020-10-13. Rochester Institute of Technologyに釜山大学とTsinghua-Berkeley Shenzhen Instituteが加わった研究グループ ... もっと読む

[出典] "Mechanisms for target recognition and cleavage by the Cas12i RNA-guided endonuclease" Zhang H, Li Z, Xiao R, Chang L. Nat Struct Mol Biol 2020-09-07.  2018年にScienceオンラインで報告されたCas12iは、クラス2タイプV CRISPR-Casエンドヌクレアーゼであ ... もっと読む

[出典] "Bright fluorescent nucleic acid detection with CRISPR-Cas12a and poly(thymine) templated copper nanoparticles" Bogers JFM [..] van Leeuweb HC. Biol Methods Protoc. 2020-10-08.  Netherlands Organization for Applied Scientific Research TNOの研究 ... もっと読む

[出典] "Advances in biosensing: The CRISPR/Cas system as a new powerful tool for the detection of nucleic acids" Bonini A et al. J Pharm Biomed Anal 2020-09-24.  核酸を同定し定量するバイオセンサー (原文ではbiosensing devices)開発の主たる課題は、感度と選 ... もっと読む