[出典] Behind the Paper "A tunable, highly-efficient CRISPR-Cpf1 system" Kim Y-S. Springer Nature Research Communities Blog 2018-09-08. https://communities.springernature.com/posts/a-tunable-highly-efficient-crispr-cpf1-system [著者所属] KRIBB, Korea U ...
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タグ:Cas12a
タイセイヨウダラのゲノム編集に最適なCRISPRシステムは?
[出典] "CRISPR-Cas9/Cas12a-based genome editing in Atlantic cod (Gadus morhua )" Adrián López-Porras A [..] Johansen F-E. Aquaculture 2023-12-05. https://doi.org/10.1016/j.aquaculture.2023.740440 [著者所属] U Oslo, Nofia AS 水産養殖も持続可能性の課題 ...
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CRISPR-Cas12aはリボソームフレームシフトの制御に利用可能であり、抗ウイルス療法の可能性も。
[出典] "Programmable modulation of ribosomal frameshifting by mRNA targeting CRISPR-Cas12a system" Huang S-H [..] Yu C-H. iScience 2023-11-16. https://doi.org/10.1016/j.isci.2023.108492 [著者所属] 成功大学, 国家衛生研究院, 台北医学大学, YD BioLabs Inc, ...
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Cas12aに全長crRNAとスプリット型crRNAを併用することで、標的DNAの検出感度向上とRNA直接検出を実現
[出典] "Asymmetric CRISPR enabling cascade signal amplification for nucleic acid detection by competitive crRNA" Moon J, Liu C. Nat Commun. 2023-11-18. https://doi.org/10.1038/s41467-023-43389-7 [著者所属] U Connecticut Health Center CRISPR技術をベースと ...
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[レビュー] CRISPR-Cas12とOMEGAシステムによるゲノム編集の最新動向
[注] OMEGA (Obligate Mobile-Element Guided Activity)[出典] Review "Recent application of CRISPR-Cas12 and OMEGA system for genome editing" Badon IW, Oh Y, Kim H-J, Lee SH. Mol Ther. 2023-11-10. https://doi.org/10.1016/j.ymthe.2023.11.013 [著者所属] 中央大 ...
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