[出典] "A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium" Tran MH [..] Mou H, Farzan M. Mol Ther Nucleic Acids 2021-02-14 [Journal Pre-proof] https://doi.org/10.1016/j.omtn.2021.02.012 Scripps研究所を主とする研究グループの成 ...
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タグ:Cas12a
複数遺伝子を対象とする多重化PCRとCas12aコラテラル活性を介して、多剤耐性アシネトバクターを高感度かつ高特異度で検出可能に
[出典] "Integration of Multiplex PCR and CRISPR-Cas Allows Highly Specific Detection of Multidrug-Resistant Acinetobacter baumannii" Wang Y [..] Li J, Xie G. Sens Actuators B Chem. 2021-02-13. https://doi.org/10.1016/j.snb.2021.129600 重慶医科大学を主と ...
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Cas12a (Cpf1)による糸状菌Aspergillus aculeatus TBRC 277の遺伝子編集
[出典] "Development of a CRISPR/Cpf1 system for targeted gene disruption in Aspergillus aculeatus TBRC 277" Abdulrachman D [..] Chantasingh D, Pootanakit K. BMC Biotechnol 2021-02-11. https://doi.org/10.1186/s12896-021-00669-8 Mahidol UniversityとタイBIO ...
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新型コロナウイルス検査法:RT-RPAとCas12aコラテラル活性を介したシグナル増幅に金ナノ粒子比色センサーの組合せ
[リンクのみ] "Reverse Transcription Recombinase Polymerase Amplification Coupled with CRISPR-Cas12a for Facile and Highly Sensitive Colorimetric SARS-CoV-2 Detection" Zhang WS [..] Yu Y, Su G. Anal Chem. 2021-02-11. https://doi.org/10.1021/acs.analchem.1c ...
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CRISPR-ENHANCE: DETECTRに手を加えて前増幅不要で核酸のフェムトモル濃度の検出感度を実現
[出典] "CRISPR-ENHANCE: An enhanced nucleic acid detection platform using Cas12a" Nguyen LT [..] Jain PK. Methods. 2021-02-09 [Journal Pre-proofs]. https://doi.org/10.1016/j.ymeth.2021.02.001 University of Floridaの研究グループの成果CRISPR ENHANCEは、LbC ...
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